1omi
From Proteopedia
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| - | [[Image:1omi.gif|left|200px]]<br /><applet load="1omi" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1omi, resolution 2.8Å" /> | ||
| - | '''Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes'''<br /> | ||
| - | == | + | ==Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes== |
| - | + | <StructureSection load='1omi' size='340' side='right'caption='[[1omi]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[ | + | <table><tr><td colspan='2'>[[1omi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OMI FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1omi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1omi OCA], [https://pdbe.org/1omi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1omi RCSB], [https://www.ebi.ac.uk/pdbsum/1omi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1omi ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1omi TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/PRFA_LISMO PRFA_LISMO] Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors. |
| - | [ | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/1omi_consurf.spt"</scriptWhenChecked> | |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [[ | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1omi ConSurf]. | |
| - | [ | + | <div style="clear:both"></div> |
| - | [[ | + | |
| - | [ | + | |
| - | + | ==See Also== | |
| + | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Listeria monocytogenes]] | ||
| + | [[Category: Almo SC]] | ||
| + | [[Category: Burley SK]] | ||
| + | [[Category: Chance MR]] | ||
| + | [[Category: Cossart P]] | ||
| + | [[Category: Dodatko T]] | ||
| + | [[Category: Fedorov AA]] | ||
| + | [[Category: Rajashankar K]] | ||
| + | [[Category: Thirumuruhan R]] | ||
Current revision
Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes
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