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1agj

From Proteopedia

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[[Image:1agj.png|left|200px]]
 
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{{STRUCTURE_1agj| PDB=1agj | SCENE= }}
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==EPIDERMOLYTIC TOXIN A FROM STAPHYLOCOCCUS AUREUS==
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<StructureSection load='1agj' size='340' side='right'caption='[[1agj]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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===EPIDERMOLYTIC TOXIN A FROM STAPHYLOCOCCUS AUREUS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1agj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AGJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9261066}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1agj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1agj OCA], [https://pdbe.org/1agj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1agj RCSB], [https://www.ebi.ac.uk/pdbsum/1agj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1agj ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1agj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AGJ OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/ETA_STAAU ETA_STAAU] Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS).<ref>PMID:2117445</ref> <ref>PMID:2384148</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:009261066</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ag/1agj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1agj ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Cavarelli, J.]]
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[[Category: Cavarelli J]]
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[[Category: Hydrolase]]
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[[Category: Serine protease]]
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Current revision

EPIDERMOLYTIC TOXIN A FROM STAPHYLOCOCCUS AUREUS

PDB ID 1agj

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