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1avo

From Proteopedia

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[[Image:1avo.png|left|200px]]
 
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{{STRUCTURE_1avo| PDB=1avo | SCENE= }}
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==PROTEASOME ACTIVATOR REG(ALPHA)==
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<StructureSection load='1avo' size='340' side='right'caption='[[1avo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===PROTEASOME ACTIVATOR REG(ALPHA)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1avo]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AVO FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9403698}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1avo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1avo OCA], [https://pdbe.org/1avo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1avo RCSB], [https://www.ebi.ac.uk/pdbsum/1avo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1avo ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1avo]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AVO OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/PSME1_HUMAN PSME1_HUMAN] Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:009403698</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/av/1avo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1avo ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hill, C P.]]
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[[Category: Large Structures]]
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[[Category: Knowlton, J R.]]
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[[Category: Hill CP]]
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[[Category: Cell adhesion]]
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[[Category: Knowlton JR]]
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[[Category: Interferon induction]]
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[[Category: Proteasome activator]]
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Current revision

PROTEASOME ACTIVATOR REG(ALPHA)

PDB ID 1avo

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OCA

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