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1bd8
From Proteopedia
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| - | [[Image:1bd8.png|left|200px]] | ||
| - | + | ==STRUCTURE OF CDK INHIBITOR P19INK4D== | |
| - | + | <StructureSection load='1bd8' size='340' side='right'caption='[[1bd8]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1bd8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BD8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bd8 OCA], [https://pdbe.org/1bd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bd8 RCSB], [https://www.ebi.ac.uk/pdbsum/1bd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bd8 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1bd8]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/CDN2D_HUMAN CDN2D_HUMAN] Interacts strongly with CDK4 and CDK6 and inhibits them.<ref>PMID:7739548</ref> <ref>PMID:8741839</ref> | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bd/1bd8_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bd8 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Baumgartner | + | [[Category: Large Structures]] |
| - | [[Category: Engh | + | [[Category: Baumgartner R]] |
| - | [[Category: Fernandez-Catalan | + | [[Category: Engh R]] |
| - | [[Category: Holak | + | [[Category: Fernandez-Catalan C]] |
| - | [[Category: Huber | + | [[Category: Holak TA]] |
| - | [[Category: Winoto | + | [[Category: Huber R]] |
| - | + | [[Category: Winoto A]] | |
| - | + | ||
| - | + | ||
Current revision
STRUCTURE OF CDK INHIBITOR P19INK4D
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