1aqr

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[[Image:1aqr.png|left|200px]]
 
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{{STRUCTURE_1aqr| PDB=1aqr | SCENE= }}
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==CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE==
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<StructureSection load='1aqr' size='340' side='right'caption='[[1aqr]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1aqr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AQR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aqr OCA], [https://pdbe.org/1aqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aqr RCSB], [https://www.ebi.ac.uk/pdbsum/1aqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aqr ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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3D solution structural calculations for yeast silver(I)-substituted metallothionein (MT) and native copper(I) MT were completed using experimentally determined NOE and dihedral angle constraints, in conjunction with experimentally derived metal-to-Cys connectivities for AgMT which were assumed identical for CuMT. For the first 40 residues in both structures, the polypeptide backbone wraps around the metal cluster in two large parallel loops separated by a deep cleft containing the metal cluster. Minor differences between the two structures include differences in hydrogen bonds and the orientation of the N-terminus with the overall protein volume conserved to within 6.5%.
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===CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE===
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3D solution structure of copper and silver-substituted yeast metallothioneins.,Peterson CW, Narula SS, Armitage IM FEBS Lett. 1996 Jan 22;379(1):85-93. PMID:8566237<ref>PMID:8566237</ref>
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{{ABSTRACT_PUBMED_8566237}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1aqr" style="background-color:#fffaf0;"></div>
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[[1aqr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQR OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:008566237</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Armitage, I M.]]
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[[Category: Armitage IM]]
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[[Category: Narula, S S.]]
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[[Category: Narula SS]]
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[[Category: Peterson, C W.]]
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[[Category: Peterson CW]]
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[[Category: Copper detoxification]]
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[[Category: Metal-thiolate cluster]]
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[[Category: Metallothionein]]
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Current revision

CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE

PDB ID 1aqr

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