1bar

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[[Image:1bar.png|left|200px]]
 
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{{STRUCTURE_1bar| PDB=1bar | SCENE= }}
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==THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS==
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<StructureSection load='1bar' size='340' side='right'caption='[[1bar]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bar]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BAR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bar OCA], [https://pdbe.org/1bar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bar RCSB], [https://www.ebi.ac.uk/pdbsum/1bar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bar ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FGF1_BOVIN FGF1_BOVIN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:9712834</ref> <ref>PMID:11039909</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/1bar_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bar ConSurf].
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<div style="clear:both"></div>
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===THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS===
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==See Also==
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*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
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{{ABSTRACT_PUBMED_1702556}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1bar]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BAR OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:001702556</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Arakawa, T.]]
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[[Category: Large Structures]]
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[[Category: Chirino, A.]]
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[[Category: Arakawa T]]
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[[Category: Faham, S.]]
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[[Category: Chirino A]]
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[[Category: Fox, G M.]]
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[[Category: Faham S]]
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[[Category: Hsu, B T.]]
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[[Category: Fox GM]]
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[[Category: Komiya, H.]]
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[[Category: Hsu BT]]
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[[Category: Rees, D C.]]
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[[Category: Komiya H]]
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[[Category: Zhu, X.]]
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[[Category: Rees DC]]
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[[Category: Growth factor]]
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[[Category: Zhu X]]

Current revision

THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS

PDB ID 1bar

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