1atg

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[[Image:1atg.gif|left|200px]]<br />
 
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<applet load="1atg" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1atg, resolution 1.2&Aring;" />
 
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'''AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN'''<br />
 
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==Overview==
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==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==
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Background:. Periplasmic receptors constitute a diverse class of binding, proteins that differ widely in size, sequence and ligand specificity., Nevertheless, almost all of them display a common beta/alpha folding motif, and have similar tertiary structures consisting of two globular domains., The ligand is bound at the bottom of a deep cleft, which lies at the, interface between these two domains. The oxyanion-binding proteins are, notable in that they can discriminate between very similar ligands., Results:. Azotobacter vinelandii is unusual in that it possesses two, periplasmic molybdate-binding proteins. The crystal structure of one of, these with bound ligand has been determined at 1.2 A resolution. It, superficially resembles the structure of sulphate-binding protein (SBP), from ... [[http://ispc.weizmann.ac.il/pmbin/getpm?9862806 (full description)]]
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<StructureSection load='1atg' size='340' side='right'caption='[[1atg]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [https://pdbe.org/1atg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [https://www.ebi.ac.uk/pdbsum/1atg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7SIH2_AZOVI Q7SIH2_AZOVI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/1atg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1atg ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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1ATG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]] with WO4, ACT, SO4 and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: MOB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]].
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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*[[ModG|ModG]]
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==Reference==
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__TOC__
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Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA., Lawson DM, Williams CE, Mitchenall LA, Pau RN, Structure. 1998 Dec 15;6(12):1529-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9862806 9862806]
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</StructureSection>
[[Category: Azotobacter vinelandii]]
[[Category: Azotobacter vinelandii]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Lawson, D.M.]]
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[[Category: Lawson DM]]
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[[Category: Mitchenall, L.A.]]
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[[Category: Mitchenall LA]]
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[[Category: Pau, R.N.]]
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[[Category: Pau RN]]
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[[Category: Williams, C.E.M.]]
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[[Category: Williams CEM]]
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[[Category: ACT]]
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[[Category: EDO]]
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[[Category: SO4]]
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[[Category: WO4]]
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[[Category: abc transporter]]
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[[Category: binding protein]]
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[[Category: molybdate]]
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[[Category: periplasm]]
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[[Category: tungstate]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:51:22 2007''
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Current revision

AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN

PDB ID 1atg

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