1c3s

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[[Image:1c3s.png|left|200px]]
 
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{{STRUCTURE_1c3s| PDB=1c3s | SCENE= }}
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==CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH SAHA==
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<StructureSection load='1c3s' size='340' side='right'caption='[[1c3s]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH SAHA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1c3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C3S FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10490031}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SHH:OCTANEDIOIC+ACID+HYDROXYAMIDE+PHENYLAMIDE'>SHH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c3s OCA], [https://pdbe.org/1c3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c3s RCSB], [https://www.ebi.ac.uk/pdbsum/1c3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c3s ProSAT]</span></td></tr>
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[[1c3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3S OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/O67135_AQUAE O67135_AQUAE]
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<ref group="xtra">PMID:010490031</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/1c3s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c3s ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Donigian, J R.]]
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[[Category: Large Structures]]
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[[Category: Finnin, M S.]]
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[[Category: Donigian JR]]
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[[Category: Pavletich, N P.]]
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[[Category: Finnin MS]]
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[[Category: Alpha/beta fold]]
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[[Category: Pavletich NP]]
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[[Category: Charge-relay system]]
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[[Category: Hydroxamic acid]]
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[[Category: Lyase]]
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[[Category: Penta-coordinated zinc]]
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Current revision

CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH SAHA

PDB ID 1c3s

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