1d1m

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[[Image:1d1m.png|left|200px]]
 
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{{STRUCTURE_1d1m| PDB=1d1m | SCENE= }}
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==CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT==
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<StructureSection load='1d1m' size='340' side='right'caption='[[1d1m]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1d1m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D1M FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10686105}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d1m OCA], [https://pdbe.org/1d1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d1m RCSB], [https://www.ebi.ac.uk/pdbsum/1d1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d1m ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1d1m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1M OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:010686105</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Enterobacteria phage lambda]]
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Check<jmol>
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[[Category: Matthews, B W.]]
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<jmolCheckbox>
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[[Category: Mollah, A K.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/1d1m_consurf.spt"</scriptWhenChecked>
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[[Category: Mossing, M C.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Rupert, P B.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Helix-turn-helix]]
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</jmolCheckbox>
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[[Category: Viral protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d1m ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Escherichia virus Lambda]]
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[[Category: Large Structures]]
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[[Category: Matthews BW]]
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[[Category: Mollah AK]]
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[[Category: Mossing MC]]
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[[Category: Rupert PB]]

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CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT

PDB ID 1d1m

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