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1ci9
From Proteopedia
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| - | [[Image:1ci9.png|left|200px]] | ||
| - | + | ==DFP-INHIBITED ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI== | |
| - | + | <StructureSection load='1ci9' size='340' side='right'caption='[[1ci9]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ci9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_gladioli Burkholderia gladioli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CI9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DFP:DIISOPROPYL+PHOSPHONATE'>DFP</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ci9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ci9 OCA], [https://pdbe.org/1ci9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ci9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ci9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ci9 ProSAT]</span></td></tr> |
| - | [[1ci9]] is a 2 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ESTB_BURGA ESTB_BURGA] Acts on short-chain (C4-C6) fatty acid esters and triglycerides, including tertiary alcohol esters. Activity on p-nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activity; it hydrolyzes the ester bond of cephalosporin substrates but there is no opening of the beta-lactam ring observed. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/1ci9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ci9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Carboxylesterase|Carboxylesterase]] | + | *[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Burkholderia gladioli]] | [[Category: Burkholderia gladioli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Kratky | + | [[Category: Kratky C]] |
| - | [[Category: Petersen | + | [[Category: Petersen EI]] |
| - | [[Category: Schwab | + | [[Category: Schwab H]] |
| - | [[Category: Wagner | + | [[Category: Wagner UG]] |
| - | + | ||
| - | + | ||
Current revision
DFP-INHIBITED ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI
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