1cqa
From Proteopedia
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| - | [[Image:1cqa.png|left|200px]] | ||
| - | + | ==BIRCH POLLEN PROFILIN== | |
| + | <StructureSection load='1cqa' size='340' side='right'caption='[[1cqa]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1cqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Betula_pendula Betula pendula]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CQA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cqa OCA], [https://pdbe.org/1cqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cqa RCSB], [https://www.ebi.ac.uk/pdbsum/1cqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cqa ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PROF1_BETPN PROF1_BETPN] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/1cqa_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cqa ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Profilin 3D Structures|Profilin 3D Structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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| - | [[ | + | |
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| - | < | + | |
[[Category: Betula pendula]] | [[Category: Betula pendula]] | ||
| - | [[Category: Almo | + | [[Category: Large Structures]] |
| - | [[Category: Ball | + | [[Category: Almo SC]] |
| - | [[Category: Fedorov | + | [[Category: Ball T]] |
| - | [[Category: Mahoney | + | [[Category: Fedorov AA]] |
| - | [[Category: Valenta | + | [[Category: Mahoney NM]] |
| - | + | [[Category: Valenta R]] | |
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Current revision
BIRCH POLLEN PROFILIN
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