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1cyd
From Proteopedia
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| - | [[Image:1cyd.png|left|200px]] | ||
| - | + | ==CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL== | |
| - | + | <StructureSection load='1cyd' size='340' side='right'caption='[[1cyd]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1cyd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CYD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CYD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cyd OCA], [https://pdbe.org/1cyd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cyd RCSB], [https://www.ebi.ac.uk/pdbsum/1cyd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cyd ProSAT]</span></td></tr> |
| - | [[1cyd]] is a 4 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CBR2_MOUSE CBR2_MOUSE] May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism.<ref>PMID:7705352</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/1cyd_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cyd ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Carbonyl reductase|Carbonyl reductase]] | *[[Carbonyl reductase|Carbonyl reductase]] | ||
| - | *[[ | + | *[[Carbonyl reductase 3D structures|Carbonyl reductase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Mitsui | + | [[Category: Mitsui Y]] |
| - | [[Category: Nonaka | + | [[Category: Nonaka T]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka N]] |
| - | + | ||
| - | + | ||
Current revision
CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL
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