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4hl8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Re-refinement of the vault ribonucleoprotein particle== | |
| - | + | <StructureSection load='4hl8' size='340' side='right'caption='[[4hl8]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4hl8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HL8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hl8 OCA], [https://pdbe.org/4hl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hl8 RCSB], [https://www.ebi.ac.uk/pdbsum/4hl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hl8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MVP_RAT MVP_RAT] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Casanas A]] | ||
| + | [[Category: Fita I]] | ||
| + | [[Category: Guerra P]] | ||
| + | [[Category: Pous J]] | ||
| + | [[Category: Querol-Audi J]] | ||
| + | [[Category: Tanaka H]] | ||
| + | [[Category: Tsukihara T]] | ||
| + | [[Category: Verdaguer V]] | ||
Current revision
Re-refinement of the vault ribonucleoprotein particle
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Categories: Large Structures | Rattus norvegicus | Casanas A | Fita I | Guerra P | Pous J | Querol-Audi J | Tanaka H | Tsukihara T | Verdaguer V
