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4drw

From Proteopedia

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[[Image:4drw.jpg|left|200px]]
 
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{{STRUCTURE_4drw| PDB=4drw | SCENE= }}
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==Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide==
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<StructureSection load='4drw' size='340' side='right'caption='[[4drw]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4drw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DRW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4drw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4drw OCA], [https://pdbe.org/4drw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4drw RCSB], [https://www.ebi.ac.uk/pdbsum/4drw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4drw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S10AA_HUMAN S10AA_HUMAN] Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.[https://www.uniprot.org/uniprot/ANXA2_HUMAN ANXA2_HUMAN] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
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===Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide===
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==See Also==
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*[[S100 proteins 3D structures|S100 proteins 3D structures]]
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{{ABSTRACT_PUBMED_22940583}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[4drw]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRW OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Junop, M S.]]
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[[Category: Large Structures]]
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[[Category: Lee, T W.]]
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[[Category: Junop MS]]
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[[Category: Rezvanpour, A.]]
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[[Category: Lee T-W]]
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[[Category: Shaw, G S.]]
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[[Category: Rezvanpour A]]
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[[Category: Atypical ef-hand]]
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[[Category: Shaw GS]]
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[[Category: Exocytosis-protein binding complex]]
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[[Category: Heteropentameric complex]]
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[[Category: Membrane repair]]
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Current revision

Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide

PDB ID 4drw

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