4h11
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy== | |
| + | <StructureSection load='4h11' size='340' side='right'caption='[[4h11]], [[Resolution|resolution]] 1.67Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4h11]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H11 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h11 OCA], [https://pdbe.org/4h11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h11 RCSB], [https://www.ebi.ac.uk/pdbsum/4h11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h11 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DLG2_RAT DLG2_RAT] Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Postsynaptic density protein 3D structures|Postsynaptic density protein 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Fiorentini M]] | ||
| + | [[Category: Gajhede M]] | ||
| + | [[Category: Kastrup JS]] | ||
Current revision
Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy
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