4h55

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[[Image:4h55.jpg|left|200px]]
 
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{{STRUCTURE_4h55| PDB=4h55 | SCENE= }}
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==Crystal structure of Canavalia brasiliensis seed lectin (ConBr) in complex with beta-d-ribofuranose==
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<StructureSection load='4h55' size='340' side='right'caption='[[4h55]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4h55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4dps 4dps]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H55 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BDR:BETA-D-RIBOFURANOSYL'>BDR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h55 OCA], [https://pdbe.org/4h55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h55 RCSB], [https://www.ebi.ac.uk/pdbsum/4h55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h55 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
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===Crystal structure of Canavalia brasiliensis seed lectin (ConBr) in complex with beta-d-ribofuranose===
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==See Also==
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*[[Concanavalin 3D structures|Concanavalin 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[4h55]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4dps 4dps]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H55 OCA].
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__TOC__
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</StructureSection>
[[Category: Canavalia brasiliensis]]
[[Category: Canavalia brasiliensis]]
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[[Category: Cavada, B S.]]
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[[Category: Large Structures]]
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[[Category: Delatorre, P.]]
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[[Category: Cavada BS]]
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[[Category: Farias, D L.]]
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[[Category: Delatorre P]]
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[[Category: Gadelha, C A.A.]]
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[[Category: Farias DL]]
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[[Category: Nobrega, R B.]]
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[[Category: Gadelha CAA]]
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[[Category: Rocha, B A.M.]]
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[[Category: Nobrega RB]]
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[[Category: Salviano, E.]]
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[[Category: Rocha BAM]]
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[[Category: Santi-Gadelha, T.]]
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[[Category: Salviano E]]
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[[Category: Silva-Filho, J C.]]
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[[Category: Santi-Gadelha T]]
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[[Category: Beta-sandwich]]
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[[Category: Silva-Filho JC]]
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[[Category: Carbohydrate-binding protein]]
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[[Category: Sugar binding protein]]
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[[Category: Sugar recognition]]
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[[Category: Sugar-binding protein]]
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Current revision

Crystal structure of Canavalia brasiliensis seed lectin (ConBr) in complex with beta-d-ribofuranose

PDB ID 4h55

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