3rrj

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[[Image:3rrj.png|left|200px]]
 
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{{STRUCTURE_3rrj| PDB=3rrj | SCENE= }}
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==Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with P1,P5-Di(adenosine-5') pentaphosphate==
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<StructureSection load='3rrj' size='340' side='right'caption='[[3rrj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with P1,P5-Di(adenosine-5') pentaphosphate===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rrj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RRJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22940582}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AP5:BIS(ADENOSINE)-5-PENTAPHOSPHATE'>AP5</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rrj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rrj OCA], [https://pdbe.org/3rrj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rrj RCSB], [https://www.ebi.ac.uk/pdbsum/3rrj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rrj ProSAT]</span></td></tr>
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[[3rrj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRJ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NNR_THEMA NNR_THEMA] Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Cymborowski, M.]]
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[[Category: Cymborowski M]]
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[[Category: Lesley, S A.]]
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[[Category: Lesley SA]]
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[[Category: Minor, W.]]
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[[Category: Minor W]]
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[[Category: Shumilin, I A.]]
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[[Category: Shumilin IA]]
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[[Category: Lyase]]
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[[Category: Unknown function]]
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Current revision

Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with P1,P5-Di(adenosine-5') pentaphosphate

PDB ID 3rrj

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