1pft
From Proteopedia
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| - | [[Image:1pft.gif|left|200px]]<br /><applet load="1pft" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1pft" /> | ||
| - | '''N-TERMINAL DOMAIN OF TFIIB, NMR'''<br /> | ||
| - | == | + | ==N-TERMINAL DOMAIN OF TFIIB, NMR== |
| - | + | <StructureSection load='1pft' size='340' side='right'caption='[[1pft]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1pft]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PFT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pft OCA], [https://pdbe.org/1pft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pft RCSB], [https://www.ebi.ac.uk/pdbsum/1pft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pft ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TF2B_PYRFU TF2B_PYRFU] Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pf/1pft_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pft ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
[[Category: Pyrococcus furiosus]] | [[Category: Pyrococcus furiosus]] | ||
| - | + | [[Category: Colangelo CM]] | |
| - | [[Category: Colangelo | + | [[Category: Lewis LM]] |
| - | [[Category: Lewis | + | [[Category: Scott RA]] |
| - | [[Category: Scott | + | [[Category: Summers MF]] |
| - | [[Category: Summers | + | [[Category: Zeng Q]] |
| - | [[Category: Zeng | + | [[Category: Zhu W]] |
| - | [[Category: Zhu | + | |
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Current revision
N-TERMINAL DOMAIN OF TFIIB, NMR
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