This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4eg4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:00, 14 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4eg4.png|left|200px]]
 
-
{{STRUCTURE_4eg4| PDB=4eg4 | SCENE= }}
+
==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1289==
-
 
+
<StructureSection load='4eg4' size='340' side='right'caption='[[4eg4]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
-
===Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1289===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4eg4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EG4 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22902861}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.151&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0OT:2-({3-[(3,5-DIBROMO-2-ETHOXYBENZYL)AMINO]PROPYL}AMINO)QUINOLIN-4(1H)-ONE'>0OT</scene>, <scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eg4 OCA], [https://pdbe.org/4eg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eg4 RCSB], [https://www.ebi.ac.uk/pdbsum/4eg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eg4 ProSAT]</span></td></tr>
-
[[4eg4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_strain_927/4_gutat10.1 Trypanosoma brucei brucei strain 927/4 gutat10.1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EG4 OCA].
+
</table>
-
[[Category: Methionine--tRNA ligase]]
+
== Function ==
-
[[Category: Trypanosoma brucei brucei strain 927/4 gutat10 1]]
+
[https://www.uniprot.org/uniprot/Q38C91_TRYB2 Q38C91_TRYB2]
-
[[Category: Fan, E.]]
+
__TOC__
-
[[Category: Hol, W G.J.]]
+
</StructureSection>
-
[[Category: Kim, J E.]]
+
[[Category: Large Structures]]
-
[[Category: Koh, C Y.]]
+
[[Category: Trypanosoma brucei brucei TREU927]]
-
[[Category: Shibata, S.]]
+
[[Category: Fan E]]
-
[[Category: Verlinde, C L.M J.]]
+
[[Category: Hol WGJ]]
-
[[Category: Aar]]
+
[[Category: Kim JE]]
-
[[Category: Aminoacyl-trna synthetase]]
+
[[Category: Koh CY]]
-
[[Category: Ligase]]
+
[[Category: Shibata S]]
-
[[Category: Ligase-ligase inhibitor complex]]
+
[[Category: Verlinde CLMJ]]
-
[[Category: Metr]]
+
-
[[Category: Nucleotide binding]]
+
-
[[Category: Parasite]]
+
-
[[Category: Protein-inhibitor complex]]
+
-
[[Category: Rossmann fold]]
+
-
[[Category: Rossmann-fold]]
+
-
[[Category: Translation]]
+
-
[[Category: Trna binding atp binding]]
+

Current revision

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1289

PDB ID 4eg4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools