1dqn

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[[Image:1dqn.png|left|200px]]
 
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{{STRUCTURE_1dqn| PDB=1dqn | SCENE= }}
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==CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE==
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<StructureSection load='1dqn' size='340' side='right'caption='[[1dqn]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dqn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DQN FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMU:PHOSPHORIC+ACID+MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL]+ESTER'>IMU</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dqn OCA], [https://pdbe.org/1dqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dqn RCSB], [https://www.ebi.ac.uk/pdbsum/1dqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dqn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q24973_GIAIN Q24973_GIAIN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dq/1dqn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dqn ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE===
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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{{ABSTRACT_PUBMED_10841757}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[1dqn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQN OCA].
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==Reference==
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<ref group="xtra">PMID:010841757</ref><references group="xtra"/>
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[[Category: Giardia intestinalis]]
[[Category: Giardia intestinalis]]
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[[Category: Hypoxanthine phosphoribosyltransferase]]
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[[Category: Large Structures]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Furneaux, R H.]]
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[[Category: Furneaux RH]]
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[[Category: Grubmeyer, C.]]
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[[Category: Grubmeyer C]]
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[[Category: Li, C M.]]
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[[Category: Li CM]]
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[[Category: Munagala, N R.]]
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[[Category: Munagala NR]]
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[[Category: Schramm, V L.]]
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[[Category: Schramm VL]]
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[[Category: Shi, W.]]
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[[Category: Shi W]]
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[[Category: Tyler, P C.]]
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[[Category: Tyler PC]]
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[[Category: Wang, C C.]]
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[[Category: Wang CC]]
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[[Category: Mg ion]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Pyrophosphate]]
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[[Category: Transferase]]
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[[Category: Transition state analogue]]
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Current revision

CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE

PDB ID 1dqn

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