1du0

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[[Image:1du0.png|left|200px]]
 
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{{STRUCTURE_1du0| PDB=1du0 | SCENE= }}
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==ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX==
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<StructureSection load='1du0' size='340' side='right'caption='[[1du0]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1du0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DU0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10889025}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1du0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1du0 OCA], [https://pdbe.org/1du0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1du0 RCSB], [https://www.ebi.ac.uk/pdbsum/1du0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1du0 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1du0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DU0 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:010889025</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/1du0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1du0 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Grant, R A.]]
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[[Category: Large Structures]]
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[[Category: Klemm, J D.]]
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[[Category: Grant RA]]
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[[Category: Pabo, C O.]]
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[[Category: Klemm JD]]
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[[Category: Rould, M A.]]
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[[Category: Pabo CO]]
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[[Category: Dna-binding protein]]
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[[Category: Rould MA]]
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[[Category: Homeodomain]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription-dna complex]]
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Current revision

ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX

PDB ID 1du0

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