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4a4q
From Proteopedia
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| - | [[Image:4a4q.jpg|left|200px]] | ||
| - | + | ==Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors== | |
| + | <StructureSection load='4a4q' size='340' side='right'caption='[[4a4q]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4a4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UX9:METHYL+[(2S)-1-{2-(2-{(3R,4S)-3-BENZYL-4-HYDROXY-1-[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]-2-OXOPYRROLIDIN-3-YL}ETHYL)-2-[4-(PYRIDIN-4-YL)BENZYL]HYDRAZINYL}-3,3-DIMETHYL-1-OXOBUTAN-2-YL]CARBAMATE'>UX9</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4q OCA], [https://pdbe.org/4a4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4q RCSB], [https://www.ebi.ac.uk/pdbsum/4a4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q8Q3H0_9HIV1 Q8Q3H0_9HIV1] | ||
| - | == | + | ==See Also== |
| - | + | *[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | |
| - | + | ||
[[Category: Human immunodeficiency virus]] | [[Category: Human immunodeficiency virus]] | ||
| - | [[Category: Arvela | + | [[Category: Large Structures]] |
| - | [[Category: Joshi | + | [[Category: Arvela RK]] |
| - | [[Category: Larhed | + | [[Category: Joshi AA]] |
| - | [[Category: Ohrngren | + | [[Category: Larhed M]] |
| - | [[Category: Persson | + | [[Category: Ohrngren P]] |
| - | [[Category: Rosenquist | + | [[Category: Persson M]] |
| - | [[Category: Samuelsson | + | [[Category: Rosenquist A]] |
| - | [[Category: Trejos | + | [[Category: Samuelsson B]] |
| - | [[Category: Unge | + | [[Category: Trejos A]] |
| - | [[Category: Vrang | + | [[Category: Unge J]] |
| - | [[Category: Wallberg | + | [[Category: Vrang L]] |
| - | [[Category: Wu | + | [[Category: Wallberg H]] |
| - | + | [[Category: Wu X]] | |
| - | + | ||
| - | + | ||
Current revision
Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors
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Categories: Human immunodeficiency virus | Large Structures | Arvela RK | Joshi AA | Larhed M | Ohrngren P | Persson M | Rosenquist A | Samuelsson B | Trejos A | Unge J | Vrang L | Wallberg H | Wu X
