1ego

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[[Image:1ego.png|left|200px]]
 
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{{STRUCTURE_1ego| PDB=1ego | SCENE= }}
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==NMR STRUCTURE OF OXIDIZED ESCHERICHIA COLI GLUTAREDOXIN: COMPARISON WITH REDUCED E. COLI GLUTAREDOXIN AND FUNCTIONALLY RELATED PROTEINS==
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<StructureSection load='1ego' size='340' side='right'caption='[[1ego]]' scene=''>
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===NMR STRUCTURE OF OXIDIZED ESCHERICHIA COLI GLUTAREDOXIN: COMPARISON WITH REDUCED E. COLI GLUTAREDOXIN AND FUNCTIONALLY RELATED PROTEINS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ego]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EGO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ego FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ego OCA], [https://pdbe.org/1ego PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ego RCSB], [https://www.ebi.ac.uk/pdbsum/1ego PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ego ProSAT]</span></td></tr>
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[[1ego]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGO OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/GLRX1_ECOLI GLRX1_ECOLI] The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase.
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<ref group="xtra">PMID:001304339</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/1ego_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ego ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Billeter, M.]]
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[[Category: Large Structures]]
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[[Category: Bjornberg, O.]]
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[[Category: Billeter M]]
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[[Category: Bushweller, J H.]]
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[[Category: Bjornberg O]]
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[[Category: Holmgren, A.]]
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[[Category: Bushweller JH]]
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[[Category: Sodano, P.]]
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[[Category: Holmgren A]]
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[[Category: Wuthrich, K.]]
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[[Category: Sodano P]]
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[[Category: Xia, T H.]]
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[[Category: Wuthrich K]]
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[[Category: Electron transport]]
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[[Category: Xia T-H]]

Current revision

NMR STRUCTURE OF OXIDIZED ESCHERICHIA COLI GLUTAREDOXIN: COMPARISON WITH REDUCED E. COLI GLUTAREDOXIN AND FUNCTIONALLY RELATED PROTEINS

PDB ID 1ego

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