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1pzc

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[[Image:1pzc.gif|left|200px]]<br /><applet load="1pzc" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1pzc, resolution 1.85&Aring;" />
 
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'''APO-PSEUDOAZURIN (METAL FREE PROTEIN)'''<br />
 
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==Overview==
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==APO-PSEUDOAZURIN (METAL FREE PROTEIN)==
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The 3D structure of the apo-pseudoazurin (copper free pseudoazurin) from Alcaligenes faecalis strain S-6 is determined and refined at pH 6.7 using X-ray diffraction data to 1.85 A resolution. The final crystallographic R-factor is 0.164. Comparing the structures of apo-pseudoazurin and the native (Cu2+) protein, we observed limited differences ranging between 0.1-0.4 A at the vicinity of the copper site, at the loops connecting the secondary structural elements, at certain beta-strands and at the amino and carboxy termini of the protein.
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<StructureSection load='1pzc' size='340' side='right'caption='[[1pzc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1pzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PZC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzc OCA], [https://pdbe.org/1pzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pzc RCSB], [https://www.ebi.ac.uk/pdbsum/1pzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pzc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AZUP_ALCFA AZUP_ALCFA] This soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen. Serves as a direct electron donor to the nitrite reductase.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pzc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pzc ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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1PZC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Alcaligenes_faecalis Alcaligenes faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZC OCA].
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*[[Pseudoazurin|Pseudoazurin]]
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__TOC__
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==Reference==
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</StructureSection>
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The crystal structure of apo-pseudoazurin from Alcaligenes faecalis S-6., Petratos K, Papadovasilaki M, Dauter Z, FEBS Lett. 1995 Jul 24;368(3):432-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7635192 7635192]
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[[Category: Alcaligenes faecalis]]
[[Category: Alcaligenes faecalis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Petratos, K.]]
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[[Category: Petratos K]]
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[[Category: apoprotein]]
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[[Category: metal free protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:34:10 2008''
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Current revision

APO-PSEUDOAZURIN (METAL FREE PROTEIN)

PDB ID 1pzc

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