Phage integrase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:20, 5 September 2018) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1z1g.png|left|200px|thumb|Crystal Structure of Enterobacteria phage λ integrase [[1z1g]]]]
+
<StructureSection load='' size='400' side='right' scene='44/443479/Cv/2' caption='Se-Met Enterobacteria phage λ integrase:DNA tetramer complex (Holiday Junction) [[1z1g]]' pspeed='8'>
-
{{STRUCTURE_1z1g| PDB=1z1g | SIZE=400| SCENE=Phage_integrase/Cv/1 |right|CAPTION= Se-Met Enterobacteria phage λ integrase:DNA tetramer complex (Holiday Junction) [[1z1g]] }}
+
 +
'''Phage integrase''' (PIN) mediates recombination between DNA recognition sequences - the phage attachment site attP and the bacterial attachment site attB<ref>PMID:14687564</ref>. The '''Tyrosine family PIN''' uses a catalytic tyrosine to mediate strand cleavage while the '''Serine family PIN''' uses a serine residue. The High-Pathogenicity Island (HPI) is a genomic island essential for virulence of the family of Enterobacteria.
 +
*The biological assembly of Enterobacteria phage λ integrase is <scene name='44/443479/Cv/3'>homotetramer</scene>.
 +
</StructureSection>
 +
== 3D Structures of phage integrase see [[Retroviral Integrase]]==
-
 
+
== References ==
-
 
+
<references/>
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
 
+
-
'''Phage integrase''' (PIN) mediate recombination between DNA recognition sequences - the phage attP and the bacterial attB. The Tyrosine family PIN uses a catalytic tyrosine to mediate strand cleavage while the Serine family PIN uses a serine residue. The High-Pathogenicity Island (HPI) is a genomic island essential for virulence of the family of Enterobacteria.
+
-
 
+
-
{{TOC limit|limit=2}}
+
-
 
+
-
== 3D Structures of phage integrase ==
+
-
 
+
-
''Update June 2011''
+
-
 
+
-
[[3nrw]] – PIN/site-specific recombinase N-terminal – ''Haloarcula marismortui''<br />
+
-
[[3jtz]] – PIN arm-type binding domain – ''Yersinia pestis''<br />
+
-
[[3ju0]] – HPI PIN arm-type binding domain – ''Pectobacterium atrosepticum''<br />
+
-
[[2kkp]] – PIN SAM-like domain – ''Moorella thermoacetica'' – NMR<br />
+
-
[[2kkv]] – PIN fragment – ''Salmonella enterica'' – NMR<br />
+
-
[[2khq]] - PIN fragment – ''Staphylococcus saprophyticus'' – NMR<br />
+
-
[[2wcc]] – λPIN DBD+ DNA – Enterobacteria phage λ - NMR<br />
+
-
[[1kjk]] – λPIN N-terminal - NMR<br />
+
-
[[2oxo]], [[1z19]], [[1z1b]] - λPIN core binding domain + DNA<br />
+
-
[[1ae9]] - λPIN catalytic core domain (mutant) <br />
+
-
[[1z1g]] – λPIN + DNA (Holliday junction)<br />
+
-
[[1p7d]] – λPIN fragment + DNA <br />
+
-
[[3bvp]] – PIN catalytic core domain – Lactococcus phage TP101-1<br />
+
-
[[1aih]] - PIN catalytic core domain – Haemophilus phage HP1<br />
+
-
[[2khv]], [[2kj5]] – PIN residues 102-199 – ''Nitrosospira multiformis'' - NMR
+
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Se-Met Enterobacteria phage λ integrase:DNA tetramer complex (Holiday Junction) 1z1g

Drag the structure with the mouse to rotate

3D Structures of phage integrase see Retroviral Integrase

References

  1. ↑ Groth AC, Calos MP. Phage integrases: biology and applications. J Mol Biol. 2004 Jan 16;335(3):667-78. PMID:14687564 doi:http://dx.doi.org/10.1016/S0022283603013561

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Phage_integrase"
Personal tools