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2m0g
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition== | |
| - | + | <StructureSection load='2m0g' size='340' side='right'caption='[[2m0g]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2m0g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0g OCA], [https://pdbe.org/2m0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0g RCSB], [https://www.ebi.ac.uk/pdbsum/2m0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0g ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SF01_HUMAN SF01_HUMAN] Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.<ref>PMID:8752089</ref> <ref>PMID:10449420</ref> <ref>PMID:9660765</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bagdiul I]] | ||
| + | [[Category: Kang H]] | ||
| + | [[Category: Kern T]] | ||
| + | [[Category: Kraemer A]] | ||
| + | [[Category: Madl T]] | ||
| + | [[Category: Maeusbacher N]] | ||
| + | [[Category: Sattler M]] | ||
| + | [[Category: Sieber SA]] | ||
| + | [[Category: Zhang Y]] | ||
| + | [[Category: Zou P]] | ||
Current revision
Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition
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Categories: Homo sapiens | Large Structures | Bagdiul I | Kang H | Kern T | Kraemer A | Madl T | Maeusbacher N | Sattler M | Sieber SA | Zhang Y | Zou P
