4gsj

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[[Image:4gsj.jpg|left|200px]]
 
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{{STRUCTURE_4gsj| PDB=4gsj | SCENE= }}
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==Crystal structure of Atg7 NTD K14A F16A D18A mutant==
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<StructureSection load='4gsj' size='340' side='right'caption='[[4gsj]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gsj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GSJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.695&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsj OCA], [https://pdbe.org/4gsj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gsj RCSB], [https://www.ebi.ac.uk/pdbsum/4gsj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
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===Crystal structure of Atg7 NTD K14A F16A D18A mutant===
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==See Also==
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*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[4gsj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSJ OCA].
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__TOC__
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[[Category: Saccharomyces cerevisiae s288c]]
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</StructureSection>
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[[Category: Deng, A.]]
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[[Category: Large Structures]]
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[[Category: Duda, D M.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Fenn, T D.]]
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[[Category: Deng A]]
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[[Category: Kaiser, S E.]]
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[[Category: Duda DM]]
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[[Category: Klionsky, D J.]]
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[[Category: Fenn TD]]
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[[Category: Kurinov, I.]]
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[[Category: Kaiser SE]]
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[[Category: Mao, K.]]
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[[Category: Klionsky DJ]]
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[[Category: Olszewski, J L.]]
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[[Category: Kurinov I]]
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[[Category: Schulman, B A.]]
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[[Category: Mao K]]
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[[Category: Taherbhoy, A M.]]
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[[Category: Olszewski JL]]
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[[Category: Yu, S.]]
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[[Category: Schulman BA]]
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[[Category: Protein transport]]
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[[Category: Taherbhoy AM]]
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[[Category: Ubiquitin-like protein activation enzyme]]
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[[Category: Yu S]]

Current revision

Crystal structure of Atg7 NTD K14A F16A D18A mutant

PDB ID 4gsj

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