1fb5

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[[Image:1fb5.png|left|200px]]
 
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{{STRUCTURE_1fb5| PDB=1fb5 | SCENE= }}
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==LOW RESOLUTION STRUCTURE OF OVINE ORNITHINE TRANSCARBMOYLASE IN THE UNLIGANDED STATE==
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<StructureSection load='1fb5' size='340' side='right'caption='[[1fb5]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fb5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FB5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb5 OCA], [https://pdbe.org/1fb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fb5 RCSB], [https://www.ebi.ac.uk/pdbsum/1fb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fb5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OTC_SHEEP OTC_SHEEP] Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline (PubMed:14527149). The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion (Probable).<ref>PMID:14527149</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/1fb5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fb5 ConSurf].
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<div style="clear:both"></div>
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===LOW RESOLUTION STRUCTURE OF OVINE ORNITHINE TRANSCARBMOYLASE IN THE UNLIGANDED STATE===
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==See Also==
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*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[1fb5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB5 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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<ref group="xtra">PMID:014527149</ref><references group="xtra"/>
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[[Category: Ornithine carbamoyltransferase]]
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[[Category: Ovis aries]]
[[Category: Ovis aries]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Bruno, G.]]
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[[Category: Bruno G]]
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[[Category: Francescato, P.]]
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[[Category: De Gregorio A]]
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[[Category: Gregorio, A De.]]
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[[Category: Francescato P]]
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[[Category: Panzalorto, M.]]
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[[Category: Panzalorto M]]
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[[Category: Zanotti, G.]]
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[[Category: Zanotti G]]
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[[Category: Cooperativity]]
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[[Category: Ornithine]]
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[[Category: T-state]]
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[[Category: Transferase]]
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Current revision

LOW RESOLUTION STRUCTURE OF OVINE ORNITHINE TRANSCARBMOYLASE IN THE UNLIGANDED STATE

PDB ID 1fb5

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