1f7o

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[[Image:1f7o.png|left|200px]]
 
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{{STRUCTURE_1f7o| PDB=1f7o | SCENE= }}
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==CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS.==
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<StructureSection load='1f7o' size='340' side='right'caption='[[1f7o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1f7o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F7O FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f7o OCA], [https://pdbe.org/1f7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f7o RCSB], [https://www.ebi.ac.uk/pdbsum/1f7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f7o ProSAT]</span></td></tr>
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[[1f7o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7O OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
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<ref group="xtra">PMID:010957629</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/1f7o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f7o ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Feline immunodeficiency virus]]
[[Category: Feline immunodeficiency virus]]
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[[Category: DUTP diphosphatase]]
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[[Category: Large Structures]]
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[[Category: Elder, J H.]]
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[[Category: Elder JH]]
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[[Category: Prasad, G S.]]
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[[Category: Prasad GS]]
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[[Category: Stout, C D.]]
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[[Category: Stout CD]]
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[[Category: Stura, E A.]]
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[[Category: Stura EA]]
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[[Category: Eight stranded beta barrel protein]]
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[[Category: Hydrolase]]
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[[Category: Viral protein]]
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Current revision

CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS.

PDB ID 1f7o

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