Ribosomal protein L27

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[[Image:RPL27.png|left|200px|thumb|Crystal Structure of Ribosomal protein L27 ([[1v8q]])]]
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<StructureSection load='1v8q' size='350' side='right' scene='' caption='Ribosomal protein L27 complex with DTT (PDB code [[1v8q]])'>
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{{STRUCTURE_1v8q| PDB=1v8q | SIZE=300| SCENE=Ribosomal_protein_L27/Cv/1 |right|CAPTION= Monomer of the dimeric ribosomal protein L27 ([[1v8q]]) }}
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== Function ==
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'''Ribosomal protein L27''' (RPL27) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. RPL27 is located at the interface between the small and large subunits.
'''Ribosomal protein L27''' (RPL27) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. RPL27 is located at the interface between the small and large subunits.
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{{TOC limit|limit=2}}
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== Relevance ==
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RPL27 from ''Trypanosoma cruzi'' may be involved in Chagas disease<ref>PMID:12866796</ref>.
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</StructureSection>
== 3D Structures of Ribosomal protein L27 ==
== 3D Structures of Ribosomal protein L27 ==
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===RPL27===
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[1v8q]] – TtRPL27 - ''Thermus thermophilus''
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===L27 in 50S subunit+RNA===
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[[2xg0]], [[2xg2]], [[3kir]], [[3kit]], [[3kiw]], [[3kiy]] – TtRPL27 in 50S subunit+RNA fragments <br />
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[[2x9s]], [[2x9u]], [[3kni]], [[3knk]], [[3knm]], [[3kno]], [[2wrj]], [[2wrl]], [[2wro]], [[2wrr]], [[3hux]], [[3huz]], [[2wh2]], [[2wh4]], [[2wdi]], [[2wdj]], [[2wdl]], [[2wdn]], [[1vsp]], [[2v47 ]], [[2v49]], [[1vsa]], [[2hgj]], [[ 2hgq]], [[2hgu]], [[2j01]], [[2j03]], [[1yl3]], [[3mrz]], [[3ms1]], [[3i8f]], [[3i8i]], [[3i9c]], [[3i9e]], [[3f1f]], [[3f1h]], [[3d5b]], [[3d5d]], [[2b66]], [[2b9n]], [[2b9p]], [[2y0v]], [[2y0x]], [[2y0z]], [[2y11]], [[2y13]], [[2y15]], [[2y17]], [[2y19]], [[3pyo]], [[3pyr]], [[3pyt]], [[3pyv]], [[2xtg]], [[2xux]], [[2xqe]] - TtRPL27 in 50S subunit+5S RRNA+23S RRNA<br />
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[[3fin]] - TtRPL27 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM<br />
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[[2wwq]] – EcRPL27 in 50S subunit+5S RRNA+23S RRNA+mRNA+P-site tRNA – ''Escherichia coli''<br />
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[[3i1n]], [[3i1p]], [[3i1r]], [[3i1t]], [[3i20]], [[3i22]], [[3e1b]], [[3e1d]], [[3df2]], [[3df4]], [[2vhn]], [[2qov]], [[2qox]], [[2i2t]], [[2i2v]], [[1vs6]], [[1vs8]], [[2aw4]], [[2awb]], [[3oas]], [[3oat]], [[3ofd]], [[3og0]], [[3ofq]], [[1vt2]], [[1vor]], [[1vou]], [[1vow]], [[1voy]], [[1vp0]], [[1pnu]], [[1pny ]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA<br />
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[[3fik]], [[2gya]], [[2gyc]], [[3bbx]], [[1p85]], [[1p86]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM<br />
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[[3kcr]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA+preprotein translocase<br />
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[[3bbo]] - RPL27 in 50S subunit+5S RRNA+23S RRNA+4.8S RRNA – Cryo-EM – spinach<br />
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[[2zjq]], [[2zjr]], [[1nkw]] - DrRPL27 in 50S subunit+5S RRNA+23S RRNA – ''Deinococcus radiodurans''
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===L27 in 50S subunit + antibiotics===
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[[3dll]], [[2zjp]], [[3cf5]], [[1xbp]], [[1sm1]], [[1nwx]], [[1nwy]], [[3pio]], [[3pip]] - DrRPL27 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+antibiotic<br />
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[[2qam]], [[2qao]], [[2qba]], [[2qbc]], [[2qoz]], [[2qp1]], [[3ofc]], [[3ofz]], [[3ofr]], [[3orb]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA+antibiotic<br />
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[[3oh5]], [[3oh7]], [[3ohj]], [[3ohk]], [[3ohz]], [[3oi1]], [[3oi3]], [[3oi5]] - TtRPL27 in 50S subunit+5S RRNA+23S RRNA+antibiotic<br />
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===L27 in 50S subunit + ribosome releasing factor (RRF)===
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[[2qbe]], [[2qbg]], [[2qbi]], [[2qbk]], [[2z4l]], [[2z4n]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA+RRF<br />
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[[2rdo]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA+EF-G+RRF – Cryo-EM<br />
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[[1y69]] – DrPRL27 + RPL16 +5S RRNA+23S RRNA+RRF
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===L27 in 50S subunit + various proteins===
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[[2vhm]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA+PDF C-terminal helix<br />
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[[2j28]] - EcRPL27 in 50S subunit+5S RRNA+23S RRNA+signal recognition particle – Cryo-EM
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===L27 in the 60S subunit===
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[[2ftc]] - RPL27 in 60S subunit+16S RRNA – Cryo EM – bovine<br />
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[[3izr]] – wRPL27 in the 60S subunit – wheat
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[[1v8q]] – TtRPL27 - ''Thermus thermophilus''<br />
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[[1y69]] – RPL27 + RPL16 + ribosome recycling factor + 5S RRNA + 23S RRNA – ''Deinococcus radiodurans''<br />
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein L27 complex with DTT (PDB code 1v8q)

Drag the structure with the mouse to rotate

3D Structures of Ribosomal protein L27

Updated on 01-October-2017

1v8q – TtRPL27 - Thermus thermophilus
1y69 – RPL27 + RPL16 + ribosome recycling factor + 5S RRNA + 23S RRNA – Deinococcus radiodurans

References

  1. ↑ Perone D, Santos MA, Peixoto MS, Cicarelli RM. Trypanosoma cruzi: identification and characterization of a novel ribosomal protein L27 (TcrL27) that cross-reacts with an affinity-purified anti-Sm antibody. Parasitology. 2003 Jun;126(Pt 6):577-83. PMID:12866796

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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