This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1qh9
From Proteopedia
(Difference between revisions)
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1qh9.jpg|left|200px]]<br /><applet load="1qh9" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1qh9, resolution 2.5Å" /> | ||
| - | '''ENZYME-PRODUCT COMPLEX OF L-2-HALOACID DEHALOGENASE'''<br /> | ||
| - | == | + | ==ENZYME-PRODUCT COMPLEX OF L-2-HALOACID DEHALOGENASE== |
| - | + | <StructureSection load='1qh9' size='340' side='right'caption='[[1qh9]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1qh9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._YL Pseudomonas sp. YL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QH9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LAC:LACTIC+ACID'>LAC</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qh9 OCA], [https://pdbe.org/1qh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qh9 RCSB], [https://www.ebi.ac.uk/pdbsum/1qh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qh9 ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/HAD_PSEUY HAD_PSEUY] Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2. |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/1qh9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qh9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Dehalogenase 3D structures|Dehalogenase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas sp. YL]] | ||
| + | [[Category: Esaki N]] | ||
| + | [[Category: Fujii T]] | ||
| + | [[Category: Hata Y]] | ||
| + | [[Category: Kurihara T]] | ||
| + | [[Category: Li Y-F]] | ||
Current revision
ENZYME-PRODUCT COMPLEX OF L-2-HALOACID DEHALOGENASE
| |||||||||||
Categories: Large Structures | Pseudomonas sp. YL | Esaki N | Fujii T | Hata Y | Kurihara T | Li Y-F
