1fqy
From Proteopedia
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| - | [[Image:1fqy.png|left|200px]] | ||
| - | + | ==STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY== | |
| - | + | <StructureSection load='1fqy' size='340' side='right'caption='[[1fqy]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1fqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The May 2014 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aquaporin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2014_5 10.2210/rcsb_pdb/mom_2014_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FQY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fqy OCA], [https://pdbe.org/1fqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fqy RCSB], [https://www.ebi.ac.uk/pdbsum/1fqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fqy ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1fqy]] is a 1 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/AQP1_HUMAN AQP1_HUMAN] Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.<ref>PMID:1373524</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fq/1fqy_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fqy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Aquaporin|Aquaporin]] | + | *[[Aquaporin 3D structures|Aquaporin 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Aquaporin]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Agre | + | [[Category: Large Structures]] |
| - | [[Category: Engel | + | [[Category: RCSB PDB Molecule of the Month]] |
| - | [[Category: Fujiyoshi | + | [[Category: Agre P]] |
| - | [[Category: Heymann | + | [[Category: Engel A]] |
| - | [[Category: Hirai | + | [[Category: Fujiyoshi Y]] |
| - | [[Category: Mitsuoka | + | [[Category: Heymann JB]] |
| - | [[Category: Murata | + | [[Category: Hirai T]] |
| - | [[Category: Walz | + | [[Category: Mitsuoka K]] |
| - | + | [[Category: Murata K]] | |
| - | + | [[Category: Walz T]] | |
| - | + | ||
Current revision
STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY
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