1g39

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[[Image:1g39.png|left|200px]]
 
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{{STRUCTURE_1g39| PDB=1g39 | SCENE= }}
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==WILD-TYPE HNF-1ALPHA DIMERIZATION DOMAIN==
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<StructureSection load='1g39' size='340' side='right'caption='[[1g39]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
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===WILD-TYPE HNF-1ALPHA DIMERIZATION DOMAIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1g39]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G39 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11106484}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.22&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g39 OCA], [https://pdbe.org/1g39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g39 RCSB], [https://www.ebi.ac.uk/pdbsum/1g39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g39 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1g39]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G39 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/HNF1A_MOUSE HNF1A_MOUSE] Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.<ref>PMID:19289501</ref> <ref>PMID:10966642</ref>
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==Reference==
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== References ==
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<ref group="xtra">PMID:011106484</ref><references group="xtra"/>
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<references/>
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[[Category: Alber, T.]]
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__TOC__
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[[Category: Cronk, J D.]]
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</StructureSection>
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[[Category: Endrizzi, J A.]]
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[[Category: Large Structures]]
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[[Category: Holton, J.]]
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[[Category: Mus musculus]]
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[[Category: Rose, R B.]]
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[[Category: Alber T]]
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[[Category: Dimerization domain]]
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[[Category: Cronk JD]]
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[[Category: Four-helix bundle]]
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[[Category: Endrizzi JA]]
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[[Category: Transcription]]
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[[Category: Holton J]]
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[[Category: Transcription factor]]
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[[Category: Rose RB]]

Current revision

WILD-TYPE HNF-1ALPHA DIMERIZATION DOMAIN

PDB ID 1g39

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