1g8a

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[[Image:1g8a.png|left|200px]]
 
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{{STRUCTURE_1g8a| PDB=1g8a | SCENE= }}
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==PYROCOCCUS HORIKOSHII FIBRILLARIN PRE-RRNA PROCESSING PROTEIN==
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<StructureSection load='1g8a' size='340' side='right'caption='[[1g8a]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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===PYROCOCCUS HORIKOSHII FIBRILLARIN PRE-RRNA PROCESSING PROTEIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1g8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G8A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g8a OCA], [https://pdbe.org/1g8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g8a RCSB], [https://www.ebi.ac.uk/pdbsum/1g8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g8a ProSAT], [https://www.topsan.org/Proteins/BSGC/1g8a TOPSAN]</span></td></tr>
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[[1g8a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G8A OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FLPA_PYRHO FLPA_PYRHO] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/1g8a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g8a ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Boisvert DC]]
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[[Category: Boisvert, D C.]]
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[[Category: Kim SH]]
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[[Category: Kim, S H.]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Rna binding]]
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[[Category: Rna binding protein]]
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[[Category: Rrna binding]]
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[[Category: Structural genomic]]
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Current revision

PYROCOCCUS HORIKOSHII FIBRILLARIN PRE-RRNA PROCESSING PROTEIN

PDB ID 1g8a

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