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1i4t

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[[Image:1i4t.png|left|200px]]
 
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{{STRUCTURE_1i4t| PDB=1i4t | SCENE= }}
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==CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN==
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<StructureSection load='1i4t' size='340' side='right'caption='[[1i4t]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1i4t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I4T FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i4t OCA], [https://pdbe.org/1i4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i4t RCSB], [https://www.ebi.ac.uk/pdbsum/1i4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i4t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARFP2_HUMAN ARFP2_HUMAN] Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i4/1i4t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i4t ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN===
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==See Also==
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*[[Rac 3D structures|Rac 3D structures]]
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{{ABSTRACT_PUBMED_11346801}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[1i4t]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I4T OCA].
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==Reference==
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<ref group="xtra">PMID:011346801</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Gamblin, S J.]]
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[[Category: Large Structures]]
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[[Category: Justin, N.]]
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[[Category: Gamblin SJ]]
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[[Category: Smerdon, S J.]]
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[[Category: Justin N]]
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[[Category: Tarricone, C.]]
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[[Category: Smerdon SJ]]
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[[Category: Xiao, B.]]
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[[Category: Tarricone C]]
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[[Category: Complex]]
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[[Category: Xiao B]]
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[[Category: G-protein]]
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[[Category: Signaling protein]]
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Current revision

CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN

PDB ID 1i4t

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