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1hsl

From Proteopedia

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[[Image:1hsl.png|left|200px]]
 
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{{STRUCTURE_1hsl| PDB=1hsl | SCENE= }}
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==REFINED 1.89 ANGSTROMS STRUCTURE OF THE HISTIDINE-BINDING PROTEIN COMPLEXED WITH HISTIDINE AND ITS RELATIONSHIP WITH MANY OTHER ACTIVE TRANSPORT(SLASH)CHEMOSENSORY RECEPTORS==
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<StructureSection load='1hsl' size='340' side='right'caption='[[1hsl]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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===REFINED 1.89 ANGSTROMS STRUCTURE OF THE HISTIDINE-BINDING PROTEIN COMPLEXED WITH HISTIDINE AND ITS RELATIONSHIP WITH MANY OTHER ACTIVE TRANSPORT(SLASH)CHEMOSENSORY RECEPTORS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1hsl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HSL FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8161536}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HIS:HISTIDINE'>HIS</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsl OCA], [https://pdbe.org/1hsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hsl RCSB], [https://www.ebi.ac.uk/pdbsum/1hsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hsl ProSAT]</span></td></tr>
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[[1hsl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HSL OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/HISJ_ECOLI HISJ_ECOLI] Component of the high-affinity histidine permease, a binding-protein-dependent transport system. The other components are proteins HisQ, HisM, and HisP.
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<ref group="xtra">PMID:008161536</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hs/1hsl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hsl ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Quiocho, F A.]]
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[[Category: Large Structures]]
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[[Category: Trakhanov, S.]]
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[[Category: Quiocho FA]]
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[[Category: Yao, N.]]
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[[Category: Trakhanov S]]
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[[Category: Binding protein]]
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[[Category: Yao N]]

Current revision

REFINED 1.89 ANGSTROMS STRUCTURE OF THE HISTIDINE-BINDING PROTEIN COMPLEXED WITH HISTIDINE AND ITS RELATIONSHIP WITH MANY OTHER ACTIVE TRANSPORT(SLASH)CHEMOSENSORY RECEPTORS

PDB ID 1hsl

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