1gkg

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[[Image:1gkg.png|left|200px]]
 
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{{STRUCTURE_1gkg| PDB=1gkg | SCENE= }}
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==Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)==
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<StructureSection load='1gkg' size='340' side='right'caption='[[1gkg]]' scene=''>
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===STRUCTURE DETERMINATION AND RATIONAL MUTAGENESIS REVEAL BINDING SURFACE OF IMMUNE ADHERENCE RECEPTOR, CR1 (CD35)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1gkg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GKG FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11955431}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gkg OCA], [https://pdbe.org/1gkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gkg RCSB], [https://www.ebi.ac.uk/pdbsum/1gkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gkg ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1gkg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKG OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/CR1_HUMAN CR1_HUMAN] Mediates cellular binding of particles and immune complexes that have activated complement.
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:011955431</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gkg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gkg ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Atkinson, J P.]]
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[[Category: Large Structures]]
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[[Category: Barlow, P N.]]
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[[Category: Atkinson JP]]
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[[Category: Bromek, K.]]
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[[Category: Barlow PN]]
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[[Category: Hauhart, R E.]]
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[[Category: Bromek K]]
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[[Category: Krych-Goldberg, M.]]
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[[Category: Hauhart RE]]
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[[Category: Mallin, R L.]]
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[[Category: Krych-Goldberg M]]
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[[Category: Smith, B O.]]
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[[Category: Mallin RL]]
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[[Category: Uhrin, D.]]
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[[Category: Smith BO]]
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[[Category: Wang, X.]]
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[[Category: Uhrin D]]
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[[Category: Complement]]
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[[Category: Wang X]]
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[[Category: Module]]
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[[Category: Scr]]
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[[Category: Sushi]]
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Current revision

Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)

PDB ID 1gkg

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