This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1htd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:35, 27 March 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1htd.png|left|200px]]
 
-
{{STRUCTURE_1htd| PDB=1htd | SCENE= }}
+
==STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN C (HT-D)==
-
 
+
<StructureSection load='1htd' size='340' side='right'caption='[[1htd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
===STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN C (HT-D)===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1htd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HTD FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_8078901}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1htd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1htd OCA], [https://pdbe.org/1htd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1htd RCSB], [https://www.ebi.ac.uk/pdbsum/1htd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1htd ProSAT]</span></td></tr>
-
[[1htd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTD OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/VM1AD_CROAT VM1AD_CROAT] Snake venom zinc metalloproteinase that causes hemorrhage by provoking the degradation of the sub-endothelial matrix proteins (fibronectin, laminin, type IV collagen, nidogen, and gelatins).<ref>PMID:2817904</ref>
-
<ref group="xtra">PMID:008078901</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Atrolysin C]]
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/1htd_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1htd ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Crotalus atrox]]
[[Category: Crotalus atrox]]
-
[[Category: Blood, C.]]
+
[[Category: Large Structures]]
-
[[Category: Bode, W.]]
+
[[Category: Blood C]]
-
[[Category: Botos, I.]]
+
[[Category: Bode W]]
-
[[Category: Doll, R.]]
+
[[Category: Botos I]]
-
[[Category: Fox, J W.]]
+
[[Category: Doll R]]
-
[[Category: Gomis-Rueth, F X.]]
+
[[Category: Fox JW]]
-
[[Category: Meyer, E F.]]
+
[[Category: Gomis-Rueth F-X]]
-
[[Category: Njoroge, F G.]]
+
[[Category: Meyer EF]]
-
[[Category: Zhang, D.]]
+
[[Category: Njoroge FG]]
-
[[Category: Metalloprotease]]
+
[[Category: Zhang D]]

Current revision

STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN C (HT-D)

PDB ID 1htd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1htd"
Personal tools