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1g2y

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[[Image:1g2y.png|left|200px]]
 
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{{STRUCTURE_1g2y| PDB=1g2y | SCENE= }}
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==HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12==
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<StructureSection load='1g2y' size='340' side='right'caption='[[1g2y]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
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===HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1g2y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G2Y FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11106484}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g2y OCA], [https://pdbe.org/1g2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g2y RCSB], [https://www.ebi.ac.uk/pdbsum/1g2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g2y ProSAT]</span></td></tr>
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[[1g2y]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2Y OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/HNF1A_MOUSE HNF1A_MOUSE] Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.<ref>PMID:19289501</ref> <ref>PMID:10966642</ref>
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<ref group="xtra">PMID:011106484</ref><references group="xtra"/>
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== References ==
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[[Category: Alber, T.]]
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<references/>
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[[Category: Cronk, J D.]]
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__TOC__
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[[Category: Endrizzi, J A.]]
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</StructureSection>
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[[Category: Holton, J.]]
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[[Category: Large Structures]]
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[[Category: Rose, R B.]]
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[[Category: Mus musculus]]
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[[Category: Dimerization domain]]
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[[Category: Alber T]]
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[[Category: Four-helix bundle]]
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[[Category: Cronk JD]]
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[[Category: Selenomethionine]]
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[[Category: Endrizzi JA]]
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[[Category: Transcription]]
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[[Category: Holton J]]
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[[Category: Transcription factor]]
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[[Category: Rose RB]]

Current revision

HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12

PDB ID 1g2y

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