4gsl

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[[Image:4gsl.png|left|200px]]
 
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{{STRUCTURE_4gsl| PDB=4gsl | SCENE= }}
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==Crystal structure of an Atg7-Atg3 crosslinked complex==
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<StructureSection load='4gsl' size='340' side='right'caption='[[4gsl]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gsl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GSL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.703&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsl OCA], [https://pdbe.org/4gsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gsl RCSB], [https://www.ebi.ac.uk/pdbsum/4gsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
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===Crystal structure of an Atg7-Atg3 crosslinked complex===
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==See Also==
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*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]]
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{{ABSTRACT_PUBMED_23142976}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[4gsl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSL OCA].
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</StructureSection>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Large Structures]]
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[[Category: Deng, A.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Duda, D M.]]
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[[Category: Deng A]]
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[[Category: Fenn, T D.]]
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[[Category: Duda DM]]
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[[Category: Kaiser, S E.]]
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[[Category: Fenn TD]]
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[[Category: Klionsky, D J.]]
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[[Category: Kaiser SE]]
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[[Category: Kurinov, I.]]
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[[Category: Klionsky DJ]]
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[[Category: Mao, K.]]
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[[Category: Kurinov I]]
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[[Category: Olszewski, J L.]]
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[[Category: Mao K]]
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[[Category: Schulman, B A.]]
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[[Category: Olszewski JL]]
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[[Category: Taherbhoy, A M.]]
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[[Category: Schulman BA]]
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[[Category: Yu, S.]]
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[[Category: Taherbhoy AM]]
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[[Category: Protein transport]]
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[[Category: Yu S]]
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[[Category: Ubiquitin-like protein activation enzyme]]
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[[Category: Ubiquitin-like protein transfer enzyme]]
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Current revision

Crystal structure of an Atg7-Atg3 crosslinked complex

PDB ID 4gsl

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Proteopedia Page Contributors and Editors (what is this?)

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