4gn1

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[[Image:4gn1.jpg|left|200px]]
 
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{{STRUCTURE_4gn1| PDB=4gn1 | SCENE= }}
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==Crystal Structure of the RA and PH domains of Lamellipodin==
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<StructureSection load='4gn1' size='340' side='right'caption='[[4gn1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===Crystal Structure of the RA and PH domains of Lamellipodin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gn1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GN1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_23150166}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gn1 OCA], [https://pdbe.org/4gn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gn1 RCSB], [https://www.ebi.ac.uk/pdbsum/4gn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gn1 ProSAT]</span></td></tr>
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[[4gn1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GN1 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAPH1_HUMAN RAPH1_HUMAN] Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chang, Y C.E.]]
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[[Category: Large Structures]]
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[[Category: Wu, J.]]
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[[Category: Chang YCE]]
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[[Category: Cell adhesion]]
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[[Category: Wu J]]
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[[Category: Cell migration]]
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[[Category: Coiled-coil region]]
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[[Category: Cytoskeletal protein]]
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[[Category: Ena/vasp binding]]
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[[Category: Pleckstrin homology domain]]
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[[Category: Ra-ph]]
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[[Category: Ras-association domain]]
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[[Category: Signaling protein]]
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Current revision

Crystal Structure of the RA and PH domains of Lamellipodin

PDB ID 4gn1

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