4b87

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[[Image:4b87.jpg|left|200px]]
 
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{{STRUCTURE_4b87| PDB=4b87 | SCENE= }}
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==Crystal structure of human DNA cross-link repair 1A==
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<StructureSection load='4b87' size='340' side='right'caption='[[4b87]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
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===Crystal structure of human DNA cross-link repair 1A===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4b87]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B87 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[4b87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B87 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b87 OCA], [https://pdbe.org/4b87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b87 RCSB], [https://www.ebi.ac.uk/pdbsum/4b87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b87 ProSAT]</span></td></tr>
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[[Category: Allerston, C K.]]
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</table>
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[[Category: Arrowsmith, C H.]]
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== Function ==
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[[Category: Berridge, G.]]
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[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
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[[Category: Bountra, C.]]
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== References ==
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[[Category: Carpenter, E P.]]
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<references/>
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[[Category: Edwards, A.]]
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__TOC__
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[[Category: Gileadi, O.]]
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</StructureSection>
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[[Category: Kochan, G.]]
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[[Category: Homo sapiens]]
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[[Category: Krojer, T.]]
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[[Category: Large Structures]]
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[[Category: Mahajan, P.]]
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[[Category: Allerston CK]]
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[[Category: Vollmar, M.]]
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[[Category: Arrowsmith CH]]
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[[Category: Vondelft, F.]]
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[[Category: Berridge G]]
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[[Category: Yue, W W.]]
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[[Category: Bountra C]]
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[[Category: Cancer]]
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[[Category: Carpenter EP]]
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[[Category: Chemotherapy]]
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[[Category: Edwards A]]
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[[Category: Dclre]]
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[[Category: Gileadi O]]
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[[Category: Dclre1a]]
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[[Category: Kochan G]]
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[[Category: Hydrolase]]
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[[Category: Krojer T]]
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[[Category: Interstrand crosslink repair]]
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[[Category: Mahajan P]]
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[[Category: Nitrogen mustard]]
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[[Category: Vollmar M]]
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[[Category: Pso2 homolog]]
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[[Category: Yue WW]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of human DNA cross-link repair 1A

PDB ID 4b87

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