This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4b87
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:4b87.jpg|left|200px]] | ||
| - | + | ==Crystal structure of human DNA cross-link repair 1A== | |
| - | + | <StructureSection load='4b87' size='340' side='right'caption='[[4b87]], [[Resolution|resolution]] 2.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4b87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B87 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b87 OCA], [https://pdbe.org/4b87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b87 RCSB], [https://www.ebi.ac.uk/pdbsum/4b87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b87 ProSAT]</span></td></tr> |
| - | [[4b87]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B87 OCA]. | + | </table> |
| - | [[Category: Allerston, C K | + | == Function == |
| - | [[Category: Arrowsmith, C H | + | [[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref> |
| - | [[Category: Berridge, G | + | == References == |
| - | [[Category: Bountra, C | + | <references/> |
| - | [[Category: Carpenter, E P | + | __TOC__ |
| - | [[Category: Edwards, A | + | </StructureSection> |
| - | [[Category: Gileadi, O | + | [[Category: Large Structures]] |
| - | [[Category: Kochan, G | + | [[Category: Allerston, C K]] |
| - | [[Category: Krojer, T | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Mahajan, P | + | [[Category: Berridge, G]] |
| - | [[Category: Vollmar, M | + | [[Category: Bountra, C]] |
| - | + | [[Category: Carpenter, E P]] | |
| - | [[Category: Yue, W W | + | [[Category: Delft, F von]] |
| + | [[Category: Edwards, A]] | ||
| + | [[Category: Gileadi, O]] | ||
| + | [[Category: Kochan, G]] | ||
| + | [[Category: Krojer, T]] | ||
| + | [[Category: Mahajan, P]] | ||
| + | [[Category: Vollmar, M]] | ||
| + | [[Category: Yue, W W]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
[[Category: Chemotherapy]] | [[Category: Chemotherapy]] | ||
Current revision
Crystal structure of human DNA cross-link repair 1A
| |||||||||||
Categories: Large Structures | Allerston, C K | Arrowsmith, C H | Berridge, G | Bountra, C | Carpenter, E P | Delft, F von | Edwards, A | Gileadi, O | Kochan, G | Krojer, T | Mahajan, P | Vollmar, M | Yue, W W | Cancer | Chemotherapy | Dclre | Dclre1a | Hydrolase | Interstrand crosslink repair | Nitrogen mustard | Pso2 homolog
