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1icj

From Proteopedia

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[[Image:1icj.png|left|200px]]
 
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{{STRUCTURE_1icj| PDB=1icj | SCENE= }}
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==PDF PROTEIN IS CRYSTALLIZED AS NI2+ CONTAINING FORM, COCRYSTALLIZED WITH INHIBITOR POLYETHYLENE GLYCOL (PEG)==
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<StructureSection load='1icj' size='340' side='right'caption='[[1icj]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===PDF PROTEIN IS CRYSTALLIZED AS NI2+ CONTAINING FORM, COCRYSTALLIZED WITH INHIBITOR POLYETHYLENE GLYCOL (PEG)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1icj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ICJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ICJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9565550}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1icj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1icj OCA], [https://pdbe.org/1icj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1icj RCSB], [https://www.ebi.ac.uk/pdbsum/1icj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1icj ProSAT]</span></td></tr>
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[[1icj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ICJ OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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<ref group="xtra">PMID:009565550</ref><ref group="xtra">PMID:009846875</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Escherichia coli]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Formylmethionine deformylase]]
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Check<jmol>
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[[Category: Becker, A.]]
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<jmolCheckbox>
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[[Category: Kabsch, W.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/1icj_consurf.spt"</scriptWhenChecked>
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[[Category: Schlichting, I.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Schultz, S.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Wagner, A F.V.]]
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</jmolCheckbox>
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[[Category: Hydrolase]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1icj ConSurf].
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[[Category: Iron metalloprotease]]
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<div style="clear:both"></div>
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[[Category: Protein synthesis]]
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Becker A]]
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[[Category: Kabsch W]]
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[[Category: Schlichting I]]
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[[Category: Schultz S]]
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[[Category: Wagner AFV]]

Current revision

PDF PROTEIN IS CRYSTALLIZED AS NI2+ CONTAINING FORM, COCRYSTALLIZED WITH INHIBITOR POLYETHYLENE GLYCOL (PEG)

PDB ID 1icj

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