1ih5

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[[Image:1ih5.png|left|200px]]
 
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{{STRUCTURE_1ih5| PDB=1ih5 | SCENE= }}
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==CRYSTAL STRUCTURE OF AQUAPORIN-1==
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<StructureSection load='1ih5' size='340' side='right'caption='[[1ih5]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF AQUAPORIN-1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ih5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hw0 1hw0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11171962}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih5 OCA], [https://pdbe.org/1ih5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih5 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1ih5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hw0 1hw0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH5 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/AQP1_HUMAN AQP1_HUMAN] Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.<ref>PMID:1373524</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/1ih5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ih5 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aquaporin|Aquaporin]]
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*[[Aquaporin 3D structures|Aquaporin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011171962</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cheng, A.]]
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[[Category: Large Structures]]
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[[Category: Melnyk, P.]]
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[[Category: Cheng A]]
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[[Category: Mitra, A K.]]
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[[Category: Melnyk P]]
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[[Category: Reddy, V S.]]
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[[Category: Mitra AK]]
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[[Category: Ren, G.]]
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[[Category: Reddy VS]]
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[[Category: Membrane protein]]
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[[Category: Ren G]]
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[[Category: Two-dimensional crystal]]
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[[Category: Water channel]]
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Current revision

CRYSTAL STRUCTURE OF AQUAPORIN-1

PDB ID 1ih5

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