1im5

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[[Image:1im5.png|left|200px]]
 
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{{STRUCTURE_1im5| PDB=1im5 | SCENE= }}
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==Crystal Structure of Pyrazinamidase of Pyrococcus horikoshii in Complex with Zinc==
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<StructureSection load='1im5' size='340' side='right'caption='[[1im5]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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===Crystal Structure of Pyrazinamidase of Pyrococcus horikoshii in Complex with Zinc===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1im5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IM5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11714269}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1im5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1im5 OCA], [https://pdbe.org/1im5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1im5 RCSB], [https://www.ebi.ac.uk/pdbsum/1im5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1im5 ProSAT]</span></td></tr>
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[[1im5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IM5 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/O58727_PYRHO O58727_PYRHO]
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<ref group="xtra">PMID:011714269</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Nicotinamidase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/1im5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1im5 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Du, X.]]
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[[Category: Du X]]
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[[Category: Kim, S H.]]
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[[Category: Kim S-H]]
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[[Category: Amidase]]
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[[Category: Covalent catalysis]]
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[[Category: Cysteine hydrolase]]
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[[Category: Drug resistance]]
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[[Category: Hydrolase]]
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[[Category: Metal ion catalysis]]
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[[Category: Nicotinamidase]]
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[[Category: Pyrazinamidase]]
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[[Category: Pyrazinamide]]
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[[Category: Pza resistance]]
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[[Category: Tuberculosis]]
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Current revision

Crystal Structure of Pyrazinamidase of Pyrococcus horikoshii in Complex with Zinc

PDB ID 1im5

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