2pq5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:06, 30 August 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2pq5.png|left|200px]]
 
-
{{STRUCTURE_2pq5| PDB=2pq5 | SCENE= }}
+
==Crystal structure of Dual specificity protein phosphatase 13 (DUSP13)==
 +
<StructureSection load='2pq5' size='340' side='right'caption='[[2pq5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2pq5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PQ5 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pq5 OCA], [https://pdbe.org/2pq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pq5 RCSB], [https://www.ebi.ac.uk/pdbsum/2pq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pq5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DS13B_HUMAN DS13B_HUMAN] Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.<ref>PMID:21360282</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pq/2pq5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pq5 ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of Dual specificity protein phosphatase 13 (DUSP13)===
+
==See Also==
-
 
+
*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[2pq5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQ5 OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Barr, A.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berridge, G.]]
+
[[Category: Barr A]]
-
[[Category: Bunkoczi, G.]]
+
[[Category: Berridge G]]
-
[[Category: Burgess-Brown, N.]]
+
[[Category: Bunkoczi G]]
-
[[Category: Delft, F von.]]
+
[[Category: Burgess-Brown N]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Knapp, S.]]
+
[[Category: Knapp S]]
-
[[Category: Niesen, F.]]
+
[[Category: Niesen F]]
-
[[Category: Pantic, N.]]
+
[[Category: Pantic N]]
-
[[Category: Pike, A C.W.]]
+
[[Category: Pike ACW]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Salah E]]
-
[[Category: Salah, E.]]
+
[[Category: Savitsky P]]
-
[[Category: Savitsky, P.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Uppenberg J]]
-
[[Category: Uppenberg, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
[[Category: Von Delft F]]
-
[[Category: Dual specificity phosphatase]]
+
-
[[Category: Dusp13]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Protein phosphatase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
[[Category: Testis and skeletal muscle specific dsp]]
+

Current revision

Crystal structure of Dual specificity protein phosphatase 13 (DUSP13)

PDB ID 2pq5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2pq5"
Personal tools