2wh5

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[[Image:2wh5.png|left|200px]]
 
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{{STRUCTURE_2wh5| PDB=2wh5 | SCENE= }}
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==Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA==
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<StructureSection load='2wh5' size='340' side='right'caption='[[2wh5]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
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[[2wh5]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH5 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh5 OCA], [https://pdbe.org/2wh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACBD4_HUMAN ACBD4_HUMAN] Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/2wh5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wh5 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Chaikuad, A.]]
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[[Category: Bountra C]]
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[[Category: Delft, F Von.]]
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[[Category: Chaikuad A]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Johansson, C.]]
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[[Category: Johansson C]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann U]]
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[[Category: Roos, A K.]]
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[[Category: Roos AK]]
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[[Category: Salah, E.]]
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[[Category: Salah E]]
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[[Category: Savitsky, P.]]
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[[Category: Savitsky P]]
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[[Category: Shafqat, N.]]
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[[Category: Shafqat N]]
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[[Category: Ugochukwu, E.]]
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[[Category: Ugochukwu E]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Yue, W W.]]
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[[Category: Yue WW]]
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[[Category: Acyl-coa binding]]
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[[Category: Von Delft F]]
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[[Category: Fatty acid metabolism]]
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[[Category: Lipid binding protein]]
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[[Category: Lipid transport]]
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Current revision

Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA

PDB ID 2wh5

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