1jy5
From Proteopedia
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| - | [[Image:1jy5.png|left|200px]] | ||
| - | + | ==RNase-related protein from Calystegia sepium== | |
| + | <StructureSection load='1jy5' size='340' side='right'caption='[[1jy5]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1jy5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Calystegia_sepium Calystegia sepium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JY5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jy5 OCA], [https://pdbe.org/1jy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jy5 RCSB], [https://www.ebi.ac.uk/pdbsum/1jy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jy5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9M7C7_CALSE Q9M7C7_CALSE] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/1jy5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jy5 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The structure of a catalytically inactive RNase-related protein from Calystegia sepium (CalsepRRP) has been resolved by protein crystallography at a resolution of 2.05 A and an R factor of 20.74%. Although the protein is completely devoid of ribonuclease activity, it adopts the typical alpha + beta structure of non-base-specific RNases. Analysis of the structure revealed that two amino-acid substitutions in the 'active' P1 site, in combination with the less hydrophobic/aromatic character of the B1 base-recognition site and a completely disrupted B2 base-recognition site, might account for this complete lack of activity. | ||
| - | + | Structure of an RNase-related protein from Calystegia sepium.,Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):627-33. Epub 2002, Mar 22. PMID:11914487<ref>PMID:11914487</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 1jy5" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | < | + | </StructureSection> |
[[Category: Calystegia sepium]] | [[Category: Calystegia sepium]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Barre A]] |
| - | [[Category: | + | [[Category: De Ranter CJ]] |
| - | [[Category: | + | [[Category: Peumans WJ]] |
| - | [[Category: | + | [[Category: Rabijns A]] |
| - | [[Category: Rouge | + | [[Category: Rouge P]] |
| - | [[Category: | + | [[Category: Van Damme EJM]] |
| - | [[Category: | + | [[Category: Verboven C]] |
| - | + | ||
| - | + | ||
Current revision
RNase-related protein from Calystegia sepium
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