1k12

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[[Image:1k12.png|left|200px]]
 
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{{STRUCTURE_1k12| PDB=1k12 | SCENE= }}
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==Fucose Binding lectin==
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<StructureSection load='1k12' size='340' side='right'caption='[[1k12]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Fucose Binding lectin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1k12]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anguilla_anguilla Anguilla anguilla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K12 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12091873}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k12 OCA], [https://pdbe.org/1k12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k12 RCSB], [https://www.ebi.ac.uk/pdbsum/1k12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k12 ProSAT]</span></td></tr>
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[[1k12]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anguilla_anguilla Anguilla anguilla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K12 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/FUCL_ANGAN FUCL_ANGAN] Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.<ref>PMID:15207656</ref> <ref>PMID:12091873</ref>
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<ref group="xtra">PMID:012091873</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/1k12_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k12 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Anguilla anguilla]]
[[Category: Anguilla anguilla]]
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[[Category: Amzel, L M.]]
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[[Category: Large Structures]]
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[[Category: Bianchet, M A.]]
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[[Category: Amzel LM]]
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[[Category: Odom, E W.]]
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[[Category: Bianchet MA]]
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[[Category: Vasta, G R.]]
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[[Category: Odom EW]]
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[[Category: Beta barrel]]
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[[Category: Vasta GR]]
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[[Category: Protein carbohydrate complex]]
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[[Category: Sugar binding protein]]
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Current revision

Fucose Binding lectin

PDB ID 1k12

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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