1js1

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[[Image:1js1.png|left|200px]]
 
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{{STRUCTURE_1js1| PDB=1js1 | SCENE= }}
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==Crystal Structure of a new transcarbamylase from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution==
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<StructureSection load='1js1' size='340' side='right'caption='[[1js1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Crystal Structure of a new transcarbamylase from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1js1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JS1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JS1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12095263}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1js1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1js1 OCA], [https://pdbe.org/1js1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1js1 RCSB], [https://www.ebi.ac.uk/pdbsum/1js1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1js1 ProSAT]</span></td></tr>
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[[1js1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JS1 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/SOTC_BACTN SOTC_BACTN] Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis. Has no activity with either L-ornithine or L-aspartate as substrate. Has also no detectable AOTCase activity, being unable to convert N(2)-acetyl-L-ornithine to N(2)-acetyl-L-citrulline.[UniProtKB:E1WKT5]
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<ref group="xtra">PMID:012095263</ref><ref group="xtra">PMID:015731101</ref><ref group="xtra">PMID:016978047</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/1js1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1js1 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacteroides fragilis]]
[[Category: Bacteroides fragilis]]
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[[Category: Allewell, N M.]]
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[[Category: Large Structures]]
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[[Category: Gallegos, R.]]
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[[Category: Allewell NM]]
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[[Category: III, J DePonte.]]
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[[Category: DePonte III J]]
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[[Category: Malamy, M.]]
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[[Category: Gallegos R]]
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[[Category: Morizono, H.]]
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[[Category: Malamy M]]
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[[Category: Shi, D.]]
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[[Category: Morizono H]]
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[[Category: Tuchman, M.]]
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[[Category: Shi D]]
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[[Category: Yu, X.]]
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[[Category: Tuchman M]]
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[[Category: Alpha/beta topology]]
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[[Category: Yu X]]
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[[Category: Transferase]]
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[[Category: Two domain]]
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Current revision

Crystal Structure of a new transcarbamylase from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution

PDB ID 1js1

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